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Related terms
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    Related terms
    • U.S. Brand Names: Clomid®;Serophene®
    • Canadian Brand Names: Clomid®;Milophene®;Serophene®
    • Mexican Brand Names: Omifin;Serofene
    • Pharmacologic Category: Ovulation Stimulator;Selective Estrogen Receptor Modulator (SERM)

    • This medicine is used to help you get pregnant.
    • Clomiphene helps eggs to finish growing. It allows their release for fertilization.


    How to take

    • Use prescription as directed.
    • Follow instructions for use carefully.

    Missed Dose

    • Call healthcare provider for instructions.


    • Store at room temperature.
    • Protect from light.
    • Protect from moisture. Do not store in a bathroom or kitchen.



    • If you have an allergy to clomiphene or any other part of this medicine.
    • Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other symptoms involved.
    • If you have any of the following conditions: Liver disease, ovarian cysts, pituitary tumor, uncontrolled adrenal gland disease, uncontrolled thyroid gland disease, or unexplained vaginal bleeding.
    • If you are pregnant or may be pregnant.


    • Check medicines with healthcare provider. This medicine may not mix well with other medicines.
    • Avoid alcohol (includes wine, beer, and liquor).
    • This medicine may increase the chance of becoming pregnant with more than one baby.
    • Tell healthcare provider if you are breast-feeding.

    Side Effects

    • Hot flashes. Wearing layers of clothes or summer clothes and cool environment may help.
    • Ovarian cyst.
    • Headache.
    • Blurred vision. Use caution when driving or doing other tasks that require you to have clear vision.
    • Nausea or vomiting. Small frequent meals, frequent mouth care, sucking hard, sugar-free candy, or chewing sugar-free gum may help.
    • Belly pain.
    • For females, breast tenderness.
    • Menstrual changes. These include lots of bleeding, spotting, or bleeding between cycles.


    • Change in condition being treated. Is it better, worse, or about the same?
    • Follow up with healthcare provider.

    Contact a healthcare provider

    • If you suspect an overdose, call your local poison control center or emergency department immediately.
    • Signs of a life-threatening reaction. These include wheezing; chest tightness; fever; itching; bad cough; blue skin color; fits; or swelling of face, lips, tongue, or throat.
    • Difficulty breathing.
    • Severe belly pain.
    • Severe headache.
    • Severe nausea or vomiting.
    • Swelling or pain of leg or arm.
    • For females, if you become pregnant while taking this medicine.
    • Any rash.
    • No improvement in condition or feeling worse.

    General Statements

    • If you have a life-threatening allergy, wear allergy identification at all times.
    • Do not share your medicine with others and do not take anyone else's medicine.
    • Keep all medicine out of the reach of children and pets.
    • Most medicines can be thrown away in household trash after mixing with coffee grounds or kitty litter and sealing in a plastic bag.
    • In Canada return any unused drugs back to the pharmacy. Also, visit for more facts about the right way to get rid of unused drugs.
    • Keep a list of all your medicines (prescription, natural products, supplements, vitamins, over-the-counter) with you. Give this list to healthcare provider (doctor, nurse, nurse practitioner, pharmacist, physician assistant).
    • Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or in Canada to Health Canada's Canada Vigilance Program at 1-866-234-2345.
    • Talk with healthcare provider before starting any new medicine, including over-the-counter, natural products, or vitamins.

    Author information
    • Copyright © 1978-2010 Lexi-Comp Inc. All rights reserved.

    Copyright © 2011 Natural Standard (

    The information in this monograph is intended for informational purposes only, and is meant to help users better understand health concerns. Information is based on review of scientific research data, historical practice patterns, and clinical experience. This information should not be interpreted as specific medical advice. Users should consult with a qualified healthcare provider for specific questions regarding therapies, diagnosis and/or health conditions, prior to making therapeutic decisions.

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